The COVID-19 pandemic generates many uncertainties for everyone, but for Asia’s poor and marginalized, there is little doubt about the devastating consequences. It’s not only about unequal access to public health care, but also the loss of livelihoods that wreaks havoc in disadvantaged communities living on the edge of subsistence that are more likely to experience police abuses under the pretext of lockdown and quarantine enforcement. As second and third waves strike, the menace of this coronavirus and the high risk of letting our guard down becomes all the more evident.